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VU-1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM) with a Ki of 156 nM and an EC50 of 9
1793053-37-8
InChiKey: JOLNKYKZGYOWSY-UHFFFAOYSA-N
Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways
Phase I Study of the JAK2 V617F Inhibitor
5'-O-DMT-N4-Bz-2'-F-dC eaenol VU-1545 is a metabotropic glutamate5' O DMT N4 Bz 2' F dC is a nucleoside with protective and modification effects. Product information CAS Number: 146954 77 0 Molecular Weight: 651. 68 Formula: C37H34FN3O7 Chemical Name: N {1 [(2R,3R,4R,5R) 5 {[bis(4 methoxyphenyl)(phenyl)methoxy]methyl} 3 fluoro 4 hydroxyoxolan 2 yl] 2 oxo 1,2 dihydropyrimidin 4 yl}benzamide Smiles: COC1=CC=C(C=C1)C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1C=CC(NC(=O)C2=CC=CC=C2)=NC1=O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC InChiKey: